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Status Epillepticus Treatment

 

Treatment of Status Epilepticus: An International Survey of Experts
Riviello, JJ, Claasen J, LaRouche SM, et. al. Neuro Critical Care, 2012
Online publication:  DOI 10.1007/S12028-012-9790-1
 
Status epilepticus requires prompt control of seizure activity.
 
Such control is best obtained through a standardized systematic approach. Unfortunately, there are few prospective randomized clinical trials so expert opinion is used to develop guidelines.  
 
Based on a survey of 60 experts in treatment of status epilepticus, the consensus was to use lorazepam intravenously as initial therapy.
 
For second-line therapy the most common agents included Phenytoin-fosphenytoin, Valproate sodium, and Levetiracetam, although the latter was rarely used in children.  
 
They compared this to the published Neurocritical Care Society’s guidelines and found them to be in agreement.  

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